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Vitamin A Toxicity in Lambs

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Lambs fed excess vitamin A in milk powder had findings consistent with Vitamin A Toxicity including elevated liver vitamin A concentrations, hepatic stellate cell hypertrophy, dermatosis, and damage to growth-plate cartilage.

Species affected: Ovine

Symptoms: Abnormal forelimb curvature (angulation, deviation); Abnormal hindlimb curvature (angulation, deviation); Alopecia, thinning, shedding, easily epilated hair; Anorexia (complete, partial); Dullness, depression, lethargy, depressed, lethargic, listless; Forelimb lameness, stiffness; Foul odour (smell) skin; Generalized lameness, stiffness; Hindlimb lameness, stiffness; Hyperkeratosis; Inability to stand, prostration; Kyphosis; Moist skin (hair or feathers); Oily skin (greasy) hair or feathers; Polydipsia; Reluctant to move; Skin erythema, inflammation; Stiffness or extended neck;

Public health importance: Not applicable.

References

  1. Reichel R., et. al., 2012, “Hypervitaminosis A in lambs fed milk replacer,” Veterinary Record; 171:448 [Web Reference]
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